Which of the following best paraphrases the underlined sentence in paragraph 5?

A sustained increase in stress hormones may arise when the brain lacks energy, eventually raising the risk of heart disease or depression.

Insufficient food intake may prompt the brain to increase stress hormone production, thereby raising long-term risks of cardiovascular and mental health disorders.

When people do not consume sufficient food, the body gradually struggles to regulate stress hormones, which may contribute to chronic illness.

Skipping meals can unintentionally trigger serious conditions such as stroke or heart disease because the brain does not receive enough energy.